Glucocorticoids with different chemical structures but similar glucocorticoid receptor potency regulate subsets of common and unique genes in human trabecular meshwork cells

Glucocorticoids with different chemical structures but similar glucocorticoid receptor potency regulate subsets of common and unique genes in human trabecular meshwork cells

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BACKGROUND:In addition to their well-documented ocular therapeutic effects, glucocorticoids (GCs) can cause sight-threatening side-effects including ocular hypertension presumably via morphological and biochemical changes in trabecular meshwork (TM) cells. In the present study, we directly compared...

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Bibliographic Details
Main Authors: Nehme, Alissar, Lobenhofer, Edward, Stamer, W. D., Edelman, Jeffrey
Other Authors: Department of Biological Sciences, Allergan, Inc., Irvine, CA 92612, USA
Language:en
Published: BioMed Central 2009
Online Access:http://hdl.handle.net/10150/610038
http://arizona.openrepository.com/arizona/handle/10150/610038

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