Glucocorticoids with different chemical structures but similar glucocorticoid receptor potency regulate subsets of common and unique genes in human trabecular meshwork cells

BACKGROUND:In addition to their well-documented ocular therapeutic effects, glucocorticoids (GCs) can cause sight-threatening side-effects including ocular hypertension presumably via morphological and biochemical changes in trabecular meshwork (TM) cells. In the present study, we directly compared...

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Bibliographic Details
Main Authors: Nehme, Alissar, Lobenhofer, Edward, Stamer, W. D., Edelman, Jeffrey
Other Authors: Department of Biological Sciences, Allergan, Inc., Irvine, CA 92612, USA
Language:en
Published: BioMed Central 2009
Online Access:http://hdl.handle.net/10150/610038
http://arizona.openrepository.com/arizona/handle/10150/610038