Discovery and Biochemical Studies of Enzymes Involved in the Queuosine Biosynthetic Pathway
Queuosine (Q) is a hypermodified nucleoside present at the wobble position in the 5'-GUN-3' anticodon loop of asparagine, aspartic acid, histidine, and tyrosine encoding tRNAs. This hypermodified base contains a 7-deazapurine structure common to many antibiotics, antivirals, and antineopla...
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| Language: | en_US |
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The University of Arizona.
2014
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| Online Access: | http://hdl.handle.net/10150/337363 |