The Role Of Titin In Cardiac Function: Studies With The Mouse Model Deficient In The Splicing Factor RBM20

In the first half of this work, titin's role in cardiac function was studied using intact cardiac myocytes. The development of a carbon fiber based cell-attachment system allowed diastolic and systolic function of the isolated intact myocyte to be investigated. Addition of actomyosin inhibitor...

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Bibliographic Details
Main Author: Methawasin, Mei Methajit
Other Authors: Granzier, Hendrikus L.
Language:en_US
Published: The University of Arizona. 2014
Subjects:
Online Access:http://hdl.handle.net/10150/337266