Novel Product Formation and Substrate Specificity of the Phospholipase D Toxins in the Venom of the Sicariidae Spider Family
Venoms of the Sicariidae spider family contain phospholipase D (PLD) enzyme toxins that can cause severe dermonecrosis and even death in humans. PLD toxins are known to cleave the substrates sphingomyelin (SM) and lysophosphatidylcholine (LPC) in mammalian tissues, releasing a choline headgroup and...
| Main Author: | |
|---|---|
| Other Authors: | |
| Language: | en_US |
| Published: |
The University of Arizona.
2014
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/10150/333346 |