The Biophysics of Titin in Cardiac Health and Disease

The giant protein titin is the third myofilament in the cardiac sarcomere. It is responsible for generating passive forces in stretched myocardium and maintaining sarcomere structure. The force generation properties of titin are determined by titin's elastic springlike elements, and this disser...

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Bibliographic Details
Main Author: Anderson, Brian R.
Other Authors: Granzier, Henk
Language:en_US
Published: The University of Arizona. 2014
Subjects:
Ig
AFM
Online Access:http://hdl.handle.net/10150/319877