An Investigation of the Insulin Pathway and TDP-43 Based Amyotrophic Lateral Sclerosis

The discovery of novel pathways and therapies in disease pathology is especially compelling in fatal neurodegenerative diseases like Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig’s Disease. We have developed a Drosophila model for ALS based on the overexpression of five variants of h...

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Bibliographic Details
Main Author: Podolsky, Taylor Catherine
Other Authors: Zarnescu, Daniela C.
Language:en
Published: The University of Arizona. 2013
Online Access:http://hdl.handle.net/10150/297742