Human liver slices: An in vitro system for determination of N-acetylation and acetylator status

An in vitro system has been developed to study N-acetyltransferase (NAT) activity using human liver slices in dynamic organ culture. Acetylation of para-aminobenzoic acid (PABA) and sulfamethazine (SMZ) in the presence of human liver slices was monitored by measuring the disappearance of the parent...

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Bibliographic Details
Main Author: Gunawardhana, Lhanoo, 1959-
Other Authors: Sipes, I. Glenn
Language:en_US
Published: The University of Arizona. 1989
Subjects:
Online Access:http://hdl.handle.net/10150/291394
http://arizona.openrepository.com/arizona/handle/10150/291394