Developing Melanocortin 3 Selective Ligands through C-Terminal Modification of Melanocortin Peptides

The melanocortin 3 and 4 receptors share 58% overall amino acid identity and 76% similarity. This high level of similarity between the MC3R and the MC4R underscores the difficulties associated with developing MC3R selective ligands, and as a consequence little is known of the physiological functions...

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Bibliographic Details
Main Author: Nyberg, Joel Benjamin
Other Authors: Hruby, Victor J.
Language:en
Published: The University of Arizona. 2013
Subjects:
Online Access:http://hdl.handle.net/10150/283606