Developing Melanocortin 3 Selective Ligands through C-Terminal Modification of Melanocortin Peptides
The melanocortin 3 and 4 receptors share 58% overall amino acid identity and 76% similarity. This high level of similarity between the MC3R and the MC4R underscores the difficulties associated with developing MC3R selective ligands, and as a consequence little is known of the physiological functions...
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Language: | en |
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The University of Arizona.
2013
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Online Access: | http://hdl.handle.net/10150/283606 |