CHARACTERIZATION OF HIGH AFFINITY ACTINOMYCIN D BINDING TO EUKARYOTIC DNA

Actinomycin D in low concentrations was suggested to inhibit ribosomal RNA (rRNA) transcription via an extranucleolar mechanism. Actinomycin D was proposed to inhibit unique messenger RNAs (mRNAs) coding for proteins needed for the maintenance of rRNA transcription. According to this hypothesis acti...

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Bibliographic Details
Main Author: Khan, Manzoor Mahmood
Other Authors: Lindell, Thomas
Language:en_US
Published: The University of Arizona. 1980
Subjects:
Online Access:http://hdl.handle.net/10150/282405