Regulation of receptor-mediated phosphatidylinositol hydrolysis in AR42J rat carcinoma cells
Receptor-activated phosphatidylinositol (PtdIns) hydrolysis was examined in AR42J rat pancreatic acini. Cholecystokinin-octapeptide (CCK₈) and bombesin induced a dose-dependent accumulation of [³H] inositol monophosphate ([³H]InsP₁). Manganese (Mn²⁺), a known calcium channel blocker, did not alter b...
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| Language: | en_US |
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The University of Arizona.
1989
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| Online Access: | http://hdl.handle.net/10150/277180 |