COMPLEMENTATION BETWEEN TEMPERATURE-SENSITIVE MUTANTS OF POLIOVIRUS

Conditional lethal mutants of poliovirus type 1 (Mahoney) were generated by treatment with the mutagen hydroxylamine. Temperature-sensitive mutants were selected by the replica plating technique at temperatures of 33°C (permissive) and 39°C (restrictive). New mutants were generated to achieve a larg...

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Bibliographic Details
Main Author: Wakeford, Laura, 1956-
Language:en_US
Published: The University of Arizona. 1987
Subjects:
Online Access:http://hdl.handle.net/10150/276556
http://arizona.openrepository.com/arizona/handle/10150/276556