COMPLEMENTATION BETWEEN TEMPERATURE-SENSITIVE MUTANTS OF POLIOVIRUS
Conditional lethal mutants of poliovirus type 1 (Mahoney) were generated by treatment with the mutagen hydroxylamine. Temperature-sensitive mutants were selected by the replica plating technique at temperatures of 33°C (permissive) and 39°C (restrictive). New mutants were generated to achieve a larg...
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Language: | en_US |
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The University of Arizona.
1987
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Online Access: | http://hdl.handle.net/10150/276556 http://arizona.openrepository.com/arizona/handle/10150/276556 |