Overexpression of the Apical Sodium-Dependent Bile Acid Transporter to Replicate Necrotizing Enterocolitis in IEC-6 Cells

This study tested a method of overexpressing the apical sodium-dependent bile acid transporter (ASBT) in IEC-6 cells to replicate necrotizing enterocolitis (NEC), a gastrointestinal disease prevalent in premature infants. The expression vector pcDNA4/TO was altered to pDR1019, containing the Rattus...

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Bibliographic Details
Main Author: Rogan, Daniel Thomas
Language:en
Published: The University of Arizona. 2012
Online Access:http://hdl.handle.net/10150/271218