Oxidative DNA Damage and DNA Binding Induced by 2, 2-Bis (Bromomethyl)-1, 3-Propanediol: Possible Mode of Action Implicated in its Carcinogenicity
The studies in this dissertation research were conducted to investigate the possible mode of action by which a brominated flame retardant, 2, 2-Bis (bromomethyl)-1, 3-propanediol (BMP) causes genotoxicity. Binding of BMP to DNA and BMP induced DNA strand breaks were investigated in SV-40 immortalize...
| Main Author: | |
|---|---|
| Other Authors: | |
| Language: | en |
| Published: |
The University of Arizona.
2012
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/10150/223375 |