MUC1 Affects EGFR Trafficking and Signaling in Breast Cancer Cells
MUC1 is a large transmembrane glycoprotein that is overexpressed in about 90% of breast cancers. Importantly, MUC1 overexpression is not a mere consequence of breast tumorigenesis but can sufficiently induce breast cancer formation when overexpressed in the mammary gland. The oncogenic mechanism of...
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Language: | EN |
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The University of Arizona.
2008
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Online Access: | http://hdl.handle.net/10150/195711 |