MUC1 Affects EGFR Trafficking and Signaling in Breast Cancer Cells

MUC1 is a large transmembrane glycoprotein that is overexpressed in about 90% of breast cancers. Importantly, MUC1 overexpression is not a mere consequence of breast tumorigenesis but can sufficiently induce breast cancer formation when overexpressed in the mammary gland. The oncogenic mechanism of...

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Bibliographic Details
Main Author: El Bejjani, Rachid Michel
Other Authors: Joyce, Schdoeder A.
Language:EN
Published: The University of Arizona. 2008
Online Access:http://hdl.handle.net/10150/195711