Predicting Passive Intestinal Drug Absorption: An Interesting Relationship between Fraction Absorbed and Melting Point
Oral drug administration remains the most popular route of drug delivery. Absorption of the dissolved drug through the intestinal epithelial membrane is a prerequisite to systemic bioavailability and drug efficacy. In efforts to reduce the long lead times, attrition rates, and costs of drug discover...
Main Author: | Chu, Katherine A. |
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Other Authors: | Yalkowsky, Samuel H. |
Language: | EN |
Published: |
The University of Arizona.
2009
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Subjects: | |
Online Access: | http://hdl.handle.net/10150/195503 |
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