Predicting Passive Intestinal Drug Absorption: An Interesting Relationship between Fraction Absorbed and Melting Point

Oral drug administration remains the most popular route of drug delivery. Absorption of the dissolved drug through the intestinal epithelial membrane is a prerequisite to systemic bioavailability and drug efficacy. In efforts to reduce the long lead times, attrition rates, and costs of drug discover...

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Bibliographic Details
Main Author: Chu, Katherine A.
Other Authors: Yalkowsky, Samuel H.
Language:EN
Published: The University of Arizona. 2009
Subjects:
Online Access:http://hdl.handle.net/10150/195503