Design of Novel Cancer Therapeutics Through The Validation of PARG as a Therapeutic Target and the Evaluation of Small Molecule Inhibitors of Hypoxia-Induced Transcription

Because of the severe toxicity and limiting side effects of traditional chemotherapy, there exists a critical need to develop better-tolerated, safer drugs to treat cancer. Recent advances in our understanding of the molecular mechanisms governing carcinogenesis have ushered in a new age in drug di...

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Bibliographic Details
Main Author: Block, Katherine M.
Other Authors: Jacobson, Myron
Language:EN
Published: The University of Arizona. 2010
Subjects:
ETP
HIF
Online Access:http://hdl.handle.net/10150/194826