The Role of Glial Activation in Descending Facilitation from the Rostroventromedial Medulla (RVM) in Models of Persistent Pain

Substantial evidence shows that activation of glial cells in the spinal cord may promote central sensitization and enhancement of pain. Descending facilitation from the rostroventromedial medulla (RVM) is also recognized as a critical component in the maintenance of chronic pain states, although the...

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Bibliographic Details
Main Author: Roberts, Jill Marie
Other Authors: Porreca, Frank
Language:EN
Published: The University of Arizona. 2009
Subjects:
Online Access:http://hdl.handle.net/10150/194471