PART I. DESIGN AND SYNTHESIS OF BICYCLIC INTERNAL BETA-TURN MIMETICS AND THEIR INCORPORATION INTO BIOLOGICALLY ACTIVE LIGANDS; PART II. SYNTHESIS OF CYCLIC PEPTIDES BY RING

PART I. DESIGN AND SYNTHESIS OF BICYCLIC INTERNAL BETA-TURN MIMETICS AND THEIR INCORPORATION INTO BIOLOGICALLY ACTIVE LIGANDS; PART II. SYNTHESIS OF CYCLIC PEPTIDES BY RING

beta-Turns in many biologically active peptides are important secondary structural elements which are critical for their biological activities. Hence, it is not surprising that beta-turn based pharmacophore design including beta-turn mimetics has become a central topic in medicinal chemistry in addi...

Full description

Bibliographic Details
Main Author: Min, Byoung Joon
Other Authors: Hruby, Victor J.
Language:EN
Published: The University of Arizona. 2010
Subjects:
beta-turn mimectics
melarnocortin receptor ligands
N-acylimminium ion cyclization
neurokinin receptor ligands
opioid ligands
ring closing metathesis
Online Access:http://hdl.handle.net/10150/194081

Internet

http://hdl.handle.net/10150/194081

Similar Items