An Investigation of the Role of Silica Substrate Topography on the Tailing and Broadening of Basic Compounds in HPLC

Atomic force microscopy, Fourier transform infrared spectroscopy, high performance liquid chromatography, and UV-vis spectroscopy were used to study commercial and locally produced chromatographic silica substrates. Previous work has correlated the presence of isolated silanols with the peak tailing...

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Bibliographic Details
Main Author: Legg, Michael Antonio
Other Authors: Wirth, Mary J
Language:EN
Published: The University of Arizona. 2007
Subjects:
Online Access:http://hdl.handle.net/10150/193792