SOLUBILIZATION OF SOME POORLY SOLUBLE DRUGS BY COSOLVENTS (FORMULATION, IDEALITY, POLARITY).
The solubilities of three poorly water soluble drugs, phenytoin, diazepam and benzocaine, were measured in various cosolvent-water mixtures. The data were generally described by the relationship: log (S(m)/S(w)) = Σf₁σ₁ where S(m) is the solubility of the drug in the cosolvent-water mixture, S(w) is...
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| Language: | en |
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The University of Arizona.
1984
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| Online Access: | http://hdl.handle.net/10150/187780 |