The Reduction of the Disulfide Bonds of Ribonuclease

An investigation has been made of the role of the four disulfide bonds of bovine pancreatic ribonuclease in maintaining the protein in a biologically active form. Studies were carried out to determine the effect of reductive cleavage of these bonds on the ability of the enzyme to catalyze the hydrol...

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Bibliographic Details
Main Author: Steiner, Lisa Amelia
Other Authors: Frederic M.Richards MD
Format: Others
Language:en
Published: Yale University 2011
Subjects:
Online Access:http://ymtdl.med.yale.edu/theses/available/etd-06062011-103356/