Carbon-Carbon Bond Formation Via o-Lithiointermediates
The process of C-C bond formation via Directed ort/zo-Metalation (DoM) consists of two separate steps. Utilizing fractional equivalents of TMEDA in hydrocarbon solvents at 60°C, o-lithiation of anisole and dimethylaniline can be effected in >95% yields. The first step in the DoM process involves...
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| Format: | Others |
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TopSCHOLAR®
2004
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| Online Access: | http://digitalcommons.wku.edu/theses/512 http://digitalcommons.wku.edu/cgi/viewcontent.cgi?article=1515&context=theses |