Potential inhibitors of COPD-relevant serine proteases based on the N-amino-4-imidazolidinone scaffold

Human neutrophil elastase (HNE) and proteinase 3 (PR3) are serine proteases which play a crucial role in the pathogenesis of chronic obstructive pulmonary disease (COPD), a multifactorial disorder associated with an imbalance between the levels of COPD-relevant proteases and their physiological prot...

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Bibliographic Details
Main Author: He, Guijia
Other Authors: Groutas, William C.
Format: Others
Language:en_US
Published: Wichita State University 2010
Online Access:http://hdl.handle.net/10057/2511