Potential inhibitors of COPD-relevant serine proteases based on the N-amino-4-imidazolidinone scaffold
Human neutrophil elastase (HNE) and proteinase 3 (PR3) are serine proteases which play a crucial role in the pathogenesis of chronic obstructive pulmonary disease (COPD), a multifactorial disorder associated with an imbalance between the levels of COPD-relevant proteases and their physiological prot...
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Format: | Others |
Language: | en_US |
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Wichita State University
2010
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Online Access: | http://hdl.handle.net/10057/2511 |