Exploring Ligand Structure and Thermodynamics of the Malachite Green RNA Aptamer

RNA aptamers are in vitro sequences of RNA that have a high affinity for their target ligand. They have applications in therapeutics, biosensors and molecular machines. While the practical applications of aptamers are increasing, it is important to study their structure and thermodynamics to improve...

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Bibliographic Details
Main Author: Da Costa, Jason Bernard
Language:en
Published: 2012
Subjects:
RNA
Online Access:http://hdl.handle.net/10012/6485