Biochemical and Biophysical Investigations of Non-Zinc Dependent Glyoxalase I Enzymes

The principal methylglyoxal (MG)-detoxifying system in most living organisms is the two metalloenzyme Glyoxalase system. Glyoxalase I (GlxI) initially converts the non-enzymatically formed MG-GSH hemithioacetal to the thioester S,D-lactoylglutathione. The hydrolase, Glyoxalase II(GlxII) regenerates...

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Bibliographic Details
Main Author: Sukdeo, Nicole
Language:en
Published: 2008
Subjects:
Online Access:http://hdl.handle.net/10012/4057