Synthesis and Application of Boronic Acid Derivatives

Boronic acids are attractive synthetic intermediates and have been shown to be effective as inhibitors of various enzymes. In this project, the overarching goal is the selective inhibition of a protease present in the mitochondria known as human ClpXP. To study the potential selective inhibition of...

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Bibliographic Details
Main Author: Sun, Jing
Other Authors: Chemistry
Format: Others
Language:en_US
Published: Virginia Tech 2017
Subjects:
Online Access:http://hdl.handle.net/10919/77006
http://scholar.lib.vt.edu/theses/available/etd-05102010-144933/