Structural Basis for Dishevelled-2 Association to the Plasma Membrane

The Wingless (Wnt) signaling pathway is one of the critical developmental pathways for control of cell differentiation, proliferation, and cell growth. The DEP domain, located on the C-terminus of Dishevelled (Dvl), plays a role in cytoplasm-membrane association, which branches the canonical and non...

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Bibliographic Details
Main Author: Lucas, Andrew Thomas
Other Authors: Biology
Format: Others
Language:en_US
Published: Virginia Tech 2017
Subjects:
DEP
Online Access:http://hdl.handle.net/10919/76974
http://scholar.lib.vt.edu/theses/available/etd-04302010-134259/