Evaluation of cerebrospinal fluid biomarkers of endothelial damage and basement membrane degradation as indirect indicators of blood-brain barrier dysfunction in chronic canine hypothyroidism

A variety of neurologic illnesses including peripheral and cranial neuropathies, central vestibular disease, seizures and coma have been associated with hypothyroidism in dogs. Repeated studies have shown that there is loss of blood brain barrier (BBB) integrity in these animals. Current research ha...

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Bibliographic Details
Main Author: Pancotto, Theresa E.
Other Authors: Veterinary Medical Sciences
Format: Others
Language:en_US
Published: Virginia Tech 2017
Subjects:
dog
Online Access:http://hdl.handle.net/10919/76955
http://scholar.lib.vt.edu/theses/available/etd-04022011-122741/