Binding properties of adaptor proteins Tollip and Tom1
Adaptor proteins, like Tollip and Tom1, facilitate cellular cargo sorting through their ubiquitin-binding domains. Tollip and Tom1 bind to each other through their TBD and GAT domains, respectively, whereas Tollip interacts with phosphatidylinositol-3-phosphate (PtdIns(3)P)-containing endosomal memb...
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Virginia Tech
2016
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Online Access: | http://hdl.handle.net/10919/73814 |