A Structural Approach to Unveil the Role of BRCA1 in the Context of Transcription
The research presented in this thesis aims to uncover the intricate manner in which BRCA1 interacts with RNAP II during mRNA production utilizing a unique microchip system developed in our lab. We were first able to prove the effectiveness of our tunable system using a breast cancer model of patien...
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Virginia Tech
2016
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| Online Access: | http://hdl.handle.net/10919/64477 |