In vitro and in vivo studies on the biotransformation of β-nicotyrine, a minor tobacco alkaloid
β-Nicotyrine is a minor tobacco alkaloid found in both tobacco plants and tobacco smoke. Preliminary studies have shown that β-nicotyrine is pneumotoxic and that the toxicity is mediated via its metabolites formed in reactions catalyzed by cytochrome P-450. The in vitro metabolic fate of β-nicotyrin...
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| Format: | Others |
| Language: | en |
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Virginia Tech
2014
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| Online Access: | http://hdl.handle.net/10919/39263 http://scholar.lib.vt.edu/theses/available/etd-08272007-163623/ |