Toward a Quantitative Analysis of PARP-1 and Poly(ADP-ribosyl)ation in Cellular Senescence
Aging is a complicated and multifactorial phenomenon. Model systems involving the induction of replicative senescence in cultured cells have been indispensable in elucidating some of the mechanisms underlying this complex process. An understanding of how and why cellular senescence occurs is thus cr...
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Virginia Tech
2014
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| Online Access: | http://hdl.handle.net/10919/39180 http://scholar.lib.vt.edu/theses/available/etd-08192010-165222/ |