Synthesis of Paclitaxel Analogs

Synthesis of Paclitaxel Analogs

Paclitaxel is one of the most successful anti-cancer drugs, particularly in the treatment of breast cancer and ovarian cancer. For the investigation of the interaction between paclitaxel and MD-2 protein, and development of new antagonists for lipopolysaccharide, several C10 A-nor-paclitaxel analogs...

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Bibliographic Details
Main Author: Xu, Zhibing
Other Authors: Chemistry
Format: Others
Published: Virginia Tech 2014
Subjects:
Myelosuppression
beta-Lactam
Baccatin
Inflammation
2-Methoxyestradiol
Tubulin
Anticancer Drugs
Cancer
Paclitaxel
Antagonists
Online Access:http://hdl.handle.net/10919/35376
http://scholar.lib.vt.edu/theses/available/etd-10132010-152742/

Internet

http://hdl.handle.net/10919/35376
http://scholar.lib.vt.edu/theses/available/etd-10132010-152742/

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