Evaluation of the actin architecture in dysplastic megakaryocytes expressing the NUP98-HOXD13 leukemic fusion gene

Some myelodysplastic syndrome (MDS) patients present with macrothrombocytopenia due to impaired megakaryocyte (MK) differentiation. Transgenic mice that express the NUP98-HOXD13 (NHD13) fusion gene is a model for MDS and recapitulates the key features of MDS. The study investigated the hypothesis th...

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Bibliographic Details
Main Author: Okyere, Benjamin
Other Authors: Veterinary Medicine
Format: Others
Published: Virginia Tech 2013
Subjects:
Online Access:http://hdl.handle.net/10919/23738