FUNCTIONAL ANALYSIS OF THE P33 AND P55 DOMAINS OF THE HELICOBACTER PYLORI VACUOLATING CYTOTOXIN
Experimental and epidemiological studies have suggested that the vacuolating cytotoxin (VacA) is an important H. pylori virulence factor that contributes to the development of peptic ulceration and gastric adenocarcinoma. VacA produces a variety of structural and functional changes in eukaryotic cel...
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Language: | en |
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VANDERBILT
2004
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Online Access: | http://etd.library.vanderbilt.edu/available/etd-12042004-172836/ |