FUNCTIONAL ANALYSIS OF THE P33 AND P55 DOMAINS OF THE HELICOBACTER PYLORI VACUOLATING CYTOTOXIN

Experimental and epidemiological studies have suggested that the vacuolating cytotoxin (VacA) is an important H. pylori virulence factor that contributes to the development of peptic ulceration and gastric adenocarcinoma. VacA produces a variety of structural and functional changes in eukaryotic cel...

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Bibliographic Details
Main Author: Torres, Victor J
Other Authors: Sebastian Joyce
Format: Others
Language:en
Published: VANDERBILT 2004
Subjects:
Online Access:http://etd.library.vanderbilt.edu/available/etd-12042004-172836/