A biologically informed method for detecting associations with rare variants

Many recent studies have identified rare variants that contribute to common, complex disease. It is believed that rare variants likely have a larger effect size (compared to GWAS findings) and can act alone, in concert with other rare variants, or together with common variants. Multiple rare variant...

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Bibliographic Details
Main Author: Moore, Carrie Colleen Buchanan
Other Authors: Tricia Thornton-Wells
Format: Others
Language:en
Published: VANDERBILT 2013
Subjects:
Online Access:http://etd.library.vanderbilt.edu/available/etd-11272013-142349/