Mechanisms of Cisplatin Resistance in Triple Negative Breast Cancer

Genomic instability and deregulated proliferation are hallmarks of human tumors. Cytotoxic chemotherapeutics, including cisplatin, have been used for over forty years to combat cancers that have deregulated proliferation and alterations in DNA damage response pathways. During initial clinical invest...

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Bibliographic Details
Main Author: Pendleton, Christopher Stephen
Other Authors: Jennifer Pietenpol
Format: Others
Language:en
Published: VANDERBILT 2014
Subjects:
Online Access:http://etd.library.vanderbilt.edu/available/etd-11242014-103854/