Insights into the Human Fragile X Syndrome Gene Family Using Drosophila melanogaster
Fragile X syndrome, resulting from the loss of function of the hFMR1 gene, is the most common heritable cause of intellectual disability. The human genome also encodes two closely related paralogs: hFXR1 and hFXR2. Drosophila that lack the dFMR1 gene recapitulate FXS-associated molecular, cellular a...
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| Format: | Others |
| Language: | en |
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VANDERBILT
2011
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| Online Access: | http://etd.library.vanderbilt.edu//available/etd-11162011-224402/ |