Optimization of Polyelectrolyte Complex Production: Implications of Molecular Characteristics on Physicochemical and Biological Properties

This study focused on creating water-based, targeted, nanoparticulate polyelectrolyte complex (PEC) drug delivery vehicles. The polymeric structure of PECs allowed for integration of an anti-angiogenic, heparin binding peptide (TSP521) for cell-specific targeting to wound and tumor endothelia. React...

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Bibliographic Details
Main Author: Hartig, Sean Michael
Other Authors: G. Kane Jennings
Format: Others
Language:en
Published: VANDERBILT 2006
Subjects:
Online Access:http://etd.library.vanderbilt.edu/available/etd-11132006-135117/