The Roles of Oxidative Stress, Inflammation and Adaptive Immunity in Aortic Stiffening

Aortic stiffening is an important cause of systolic hypertension and predispose to cardiovascular morbidity and mortality. The precise mechanisms underlying aortic stiffening remain undefined. Using multiple genetically modified mouse models, I performed a series of studies to investigate the roles...

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Bibliographic Details
Main Author: Wu, Jing
Other Authors: David G. Harrison, M.D.
Format: Others
Language:en
Published: VANDERBILT 2014
Subjects:
Online Access:http://etd.library.vanderbilt.edu/available/etd-11042014-141150/