DOCKING OF THE p68 SUBUNIT OF DNA POLYMERASE ¦Á-PRIMASE ON THE SV40 HELICASE IS REQUIRED FOR THE VIRAL PRIMOSOME ACTIVITY
DNA polymerase ¦Á-primase (pol-prim) plays a central role in eukaryotic DNA replication, initiating synthesis on both the leading and lagging strand DNA templates. Pol-prim consists of a primase heterodimer that synthesizes RNA primers, a DNA polymerase that extends them, and a fourth subunit, p68,...
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Language: | en |
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VANDERBILT
2010
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Online Access: | http://etd.library.vanderbilt.edu/available/etd-11042010-114906/ |