Effects of alterations to the tumor microenvironment driven by transforming growth factor beta on tumor progression
Dissertation under the direction of Professor Harold L. Moses Transforming Growth Factor Beta (TGF-β) is acts as both a tumor suppressor and promoter in the context of epithelial tumor progression. In epithelial cells, active TGF-β signaling promotes cell cycle arrest to slow tumor growth but also p...
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| Format: | Others |
| Language: | en |
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VANDERBILT
2013
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| Online Access: | http://etd.library.vanderbilt.edu/available/etd-10092013-140015/ |