CBS Domains Regulate CLC Chloride Channel Gating: Role of the R-Helix Linker

All eukaryotic and some prokaryotic ClC anion transport proteins have extensive cytoplasmic C-termini containing two cystathionine-beta-synthase (CBS) domains. CBS domain secondary structure is highly conserved and consists of two alpha-helices and three beta-strands arranged as beta1-alpha1-beta2-b...

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Bibliographic Details
Main Author: Dave', Sonya
Other Authors: Hassane Mchaourab
Format: Others
Language:en
Published: VANDERBILT 2010
Subjects:
Online Access:http://etd.library.vanderbilt.edu/available/etd-08152010-213719/