Oxidized Low Density Lipoprotein Immune Complexes Prime the NLRP3 Inflammasome and Modulate T cell Responses in Atherosclerosis

Oxidized low-density lipoprotein (oxLDL) is known to activate inflammatory responses in a variety of cells, especially macrophages and dendritic cells. Much of the oxLDL in circulation is complexed to antibodies, and these resulting immune complexes (ICs) are a prominent feature of chronic inflammat...

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Bibliographic Details
Main Author: Rhoads, Jillian Patricia
Other Authors: Mark Boothby
Format: Others
Language:en
Published: VANDERBILT 2017
Subjects:
Online Access:http://etd.library.vanderbilt.edu/available/etd-08022017-122352/