Oxidized Low Density Lipoprotein Immune Complexes Prime the NLRP3 Inflammasome and Modulate T cell Responses in Atherosclerosis
Oxidized low-density lipoprotein (oxLDL) is known to activate inflammatory responses in a variety of cells, especially macrophages and dendritic cells. Much of the oxLDL in circulation is complexed to antibodies, and these resulting immune complexes (ICs) are a prominent feature of chronic inflammat...
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Format: | Others |
Language: | en |
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VANDERBILT
2017
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Online Access: | http://etd.library.vanderbilt.edu/available/etd-08022017-122352/ |