Structural Consequences of the C8-Guanine DNA Adduct Formed by 3-Nitrobenzanthrone; an Environmental Carcinogen

Damage to DNA results from many endogenous and exogenous sources and plays a significant role in cancer etiology. 3-Nitrobenzathrone (3-NBA) is a component of diesel exhaust that is known to form DNA adducts. Aminobenzanthrone (ABA) DNA adducts result through the reaction of electrophilic nitrenium...

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Bibliographic Details
Main Author: Politica, Dustin Alan
Other Authors: Michael P. Stone, Ph.D.
Format: Others
Language:en
Published: VANDERBILT 2016
Subjects:
Online Access:http://etd.library.vanderbilt.edu/available/etd-08012016-091632/