Intracellular Hexokinase Localization in Hybridoma Cultures: Implications for Regulation of Metabolism and Cell Death

<p>Glycolysis and apoptotic cell death are integrated by the binding of hexokinase to the mitochondria where it has been reported that hexokinase phosphorylates glucose more efficiently and impedes apoptotic protein release into the cytosol by promoting VDAC closure. Interestingly, it has also...

Full description

Bibliographic Details
Main Author: Clark, Lindsey M.
Other Authors: Kenneth Debelak
Format: Others
Language:en
Published: VANDERBILT 2005
Subjects:
Online Access:http://etd.library.vanderbilt.edu/available/etd-07222005-124121/