Spectroscopic Study of the Conformational Changes Involved in the Activation of CaMKII

The CaMKII enzyme is involved in diverse biological processes including control of heart rate and synaptic plasticity. CaMKII is activated by binding of calmodulin (CaM) and ATP. Its intricate structure and dynamics are thought to underlie its mode of self-regulation. The enzyme consists of catalyti...

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Bibliographic Details
Main Author: Rodriguez Mena, Francisco Guillermo
Other Authors: Hassane Mchaourab, Ph.D
Format: Others
Language:en
Published: VANDERBILT 2016
Subjects:
Online Access:http://etd.library.vanderbilt.edu/available/etd-07192016-152059/