Structural Studies of the Interaction between mGlu5 and Allosteric Modulators

Structural Studies of the Interaction between mGlu5 and Allosteric Modulators

The metabotropic glutamate receptor subtype 5 (mGlu5), a class C G-protein coupled receptor (GPCR), is involved in cognitive function through diverse signaling pathways that modulate synaptic plasticity. Modulators of mGlu5 hold exciting potential for the development of novel treatment strategies th...

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Bibliographic Details
Main Author:	Nguyen, Elizabeth Dong
Other Authors:	P. Jeffrey Conn, Ph.D.
Format:	Others
Language:	en
Published:	VANDERBILT 2013
Subjects:	Chemical and Physical Biology
Online Access:	http://etd.library.vanderbilt.edu/available/etd-07172013-164828/

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